Each vial contains Cefuroxime Sodium USP equivalent to Cefuroxime 750mg/1.5g.
Cefuroxime is a semisynthetic, broad-spectrum, cephalosporin antibiotic for parenteral administration.
Cefuroxime has invitro activity against a wide-range of gram-positive and gram-negative organisms and it is highly stable in the presence of beta-lactamases of certain gram negative bacteria. The bactericidal action of Cefuroxime results from inhibition of cell-wall synthesis.
The serum half-life after either IM or IV injection is approximately 80 minutes. Approximately 89% of a dose of Cefuroxime is excreted by the kidneys over an 8 hour period, resulting in high urinary concentrations. Cefuroxime is detectable in therapeutic concentrations in pleural fluid, joint fluid, bile, sputum, bone and aqueous humor. Cefuroxime is 50% bound to serum proteins.
Cefuroxime Injection is indicated for the treatment of patients with infections caused by susceptible strains of the designated organisms in the following diseases.
Zocef Injection is available in 750mg/1.5g Cefuroxime per vial.
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