Each Taxim vial contains Cefotaxime Sodium USP equivalent to Cefotaxime 250mg/500mg/1gm.
Taxim (Cefotaxime) injection is a semi synthetic, broad spectrum cephalosporin antibiotic. It is an odourless, white to slightly cream coloured powder. Taxim is freely soluble in water, insoluble in organic solvents.
IM- administration of a single 5700mg to normal volunteers mean peak serum concentrations of 11.7ug/ml was attained within 30 minutes and declined with an elimination half-life about 1 hour. About 60% of the administered dose was recovered from urine during the first 6 hours following the start of the infusion.
About 20-36% of I.V. administered during 14- Cefotaxime is secreted by the kidneys as unchanged. Cefotaxime and 15-25% as the desactyl derivative. It has shown to contribute the bactericidal activity.
Taxim is indicated for the treatment of patients with serious infections caused by susceptible strains of the designated micro-organisms.
Taxim Injection is available in 250mg/500mg/1g vial in a carton with 5ml ampoule of water for injection.
Air Jordan