Each film-coated tablet contains Cefuroxime Axetil EP equivalent to Cefuroxime 250mg or 500mg.

Cefuroxime Axetil is the 1-acetoxyehyl ester of Cefuroxime. Cefuroxime is a semi synthetic analog of cephalosporin C. Cefuroxime has in vitro activity against a wide range of gram-positive and gram-negative organisms and its highly stable in the presence of beta-lactamases of certain gram negative bacteria. The bactericidal action of Cefuroxime results from inhibition of cell-wall synthesis.

Approximately 50% of serum Cefuroxime is bound to protein.

After oral administration, Cefuroxime Axetil is absorbed from the gastrointestinal tract and rapidly hydrolyzed by nonspecific esterases in the intestinal mucosa and blood to Cefuroxime.

Cefuroxime is subsequently distributed throughout the extracellular fluids. The Axetil moiety is metabolized to acetaldehyde and acetic acid.

Cefuroxime tablets are indicated for the treatment of:-

  • Upper and lower respiratory tract infections
  • Skin and soft tissue infections
  • Urinary tract infections etc.

Cefuroxime tablets are available in blister strip of 10 tablets.

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